Horror has a new face.
A small town is taken over by an alien plague, turning residents into zombies and all forms of mutant monsters.
Slither (2006) is a horror, science fiction and comedy film directed by James Gunn, released on March 31, 2006 with a runtime of 1h 36m. It stars Nathan Fillion, Michael Rooker, Elizabeth Banks and Gregg Henry. Viewers rate it 6.5 out of 10 across 1,790 ratings.
Watch the official trailer for Slither before you stream it.
Official trailers, teasers, clips and featurettes for Slither.
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Trailer
Clip
Clip
Featurette
Featurette
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Nathan Fillion
as Bill Pardy
Michael Rooker
as Grant Grant
Elizabeth Banks
as Starla Grant
Gregg Henry
as Jack MacReady
Tania Saulnier
as Kylie Strutemyer
Don Thompson
as Wally
Brenda James
as Brenda Gutierrez
Jennifer Copping
as Margaret
Jenna Fischer
as Shelby
Haig Sutherland
as Trevor
William MacDonald
as Mr. Strutemyer
Iris Quinn
as Mrs. Strutemyer
Directed by James Gunn, written by James Gunn, produced by Paul Brooks, Eric Newman and Dan Lee West.
Average viewer score of 6.5/10 from 1,790 ratings.
A comedy-horror riff on an alien-parasite invasion of a small rural town is fun, gross and completely engaging. James Gunn demonstrates his pre-GOG chops, getting the most of the great acting ensemble including Elizabeth Banks, Michael Rooker, and Nathan Fillon.
Reviewed on October 28, 2020
OK, so some of the visual effects looked like they'd come straight from a 1970s edition of "Dr. Who", but once this gets up and running it's actually quite an entertaining bug-cum-zombie horror. When a meteorite lands outside a small American town, it's slug-like occupant manages to spore the local bigwig "Grant" (Michael Rooker) after he had sought some beer-induced woodland comfort after being spurned by his…
Reviewed on May 6, 2026
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Slither (2006) is currently available to rent or buy from Amazon Video, Apple TV Store, Google Play Movies, YouTube and Fandango At Home. No subscription streaming option is listed right now, so availability may change.
The main cast of Slither (2006) includes Nathan Fillion, Michael Rooker, Elizabeth Banks, Gregg Henry and Tania Saulnier. The film was directed by James Gunn. You can see the full cast and crew list, with character names, further up this page.
Slither was released on March 31, 2006 and runs for 1h 36m.
Slither (2006) holds an average rating of 6.5 out of 10 from 1,790 viewer votes, and is a good pick if you enjoy horror, science fiction and comedy films. Read the viewer reviews on this page to decide for yourself.
Yes. The official Slither trailer is embedded in the trailer section of this page and plays instantly, no download or sign-up required.
