Official poster for the TV series Common Side Effects (2025), a animation drama show

Common Side Effects(2025)

8.52 seasons10 episodesReturning Series
AnimationDramaComedySci-Fi & Fantasy

Common Side Effects Synopsis

Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.

Common Side Effects (2025) is a animation, drama, comedy and sci-fi & fantasy series that premiered on February 2, 2025, spanning 2 seasons and 10 episodes. It stars Dave King, Emily Pendergast, Mike Judge and Martha Kelly. Viewers rate it 8.5 out of 10 across 345 ratings.

First aired:
2025-02-02
Last aired:
2025-03-30
Producers:
Joseph Bennett, Steve Hely, James Merrill

Common Side Effects (2025) Trailer

Watch the official trailer for Common Side Effects before you start streaming.

Common Side Effects Videos & Clips

Official trailers, teasers, clips and featurettes for Common Side Effects.

Official Trailer [Adult Swim Europe]

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Official Trailer #3

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Official Trailer #2

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Promo #5

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Promo #2

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Common Side Effects Reviews & Ratings

Average viewer score of 8.5/10 from 345 ratings.

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Common Side Effects – Frequently Asked Questions

Where can I stream Common Side Effects?

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Common Side Effects (2025) is available to stream on HBO Max Amazon Channel, YouTube TV, Adult Swim and HBO Max, with episodes also available to buy from Amazon Video, Apple TV Store, Google Play Movies and Fandango At Home. Availability comes from JustWatch data and varies by country.

How many seasons of Common Side Effects are there?

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Common Side Effects has 2 seasons and 10 episodes in total, starting from its premiere on February 2, 2025.

Is Common Side Effects still running?

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Common Side Effects is currently listed as returning series, with the most recent episode airing on March 30, 2025.

Who is in the cast of Common Side Effects?

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Common Side Effects (2025) stars Dave King, Emily Pendergast, Mike Judge, Martha Kelly and Joseph Lee Anderson. The full cast list with character names is available in the cast section of this page.

Is Common Side Effects any good?

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Common Side Effects (2025) is rated 8.5 out of 10 from 345 viewer votes, and suits viewers who like animation, drama and comedy series. Reviews from viewers are collected further down this page.

Where can I watch the Common Side Effects trailer?

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The official Common Side Effects trailer is embedded in the trailer section of this page and plays instantly in your browser.